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艾乐美生物科技有限公司(AllerMAbs Co., Ltd.)成立于2015年,是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体,特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体,将有助于IgE 相关领域的研究工作。因此,AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性,经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠,通过杂交瘤技术 (Hybridoma technology),成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试,此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性,皆与人类IgE 抗体一致,研究成果于2015 年发表在国际学术期刊上。

 

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题,让嵌合人类IgE抗体可以成为人类IgE抗体的替代品,并提供一个更稳定、更符合血清IgE检测系统的校正品,让临床血清IgE的检测结果更加准确与可靠。

 

其利用动物基因转殖技术,将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes),分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置,接着把胚胎干细胞分別植入孕母鼠体内,并将其带有嵌入基因之成鼠交互配种,最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice),且体内能制造完整的嵌合人类IgE抗体分子。

 

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品

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Immunolab.png

Immunolab GmbH主要从事开发和生产各种免疫诊断试剂,可用于过敏诊断、自身免疫血清学、传染病以及食物分析等领域。在过敏诊断领域,主要产品是一系列综合过敏原的免疫球蛋白IgE、IgG、IgG1和IgG4试剂盒。

 

Founded in 1992, Immunolab started its operations as routine laboratory for allergy diagnostics. The name Immunolab originates from this task, applying immunological methods. Soon we started with the development, production and distribution of our own products. Both, food safety and IVD medical devices were covered from the very beginning. Products and processes were driven by quality thinking which resulted in the accredited establishment of our quality management system in 2002, followed by the accreditation of all IVD products according to the European legislation. As a demand of constant growth we moved to our own facility in 2007, which was extended considerably in 2015 and is equipped according to all modern standards. In 2014 Immunolab joined Biovendor group. This gave us the chance to combine all our experience and flexibility as a smaller-scale company with the opportunities of a larger network of companies.

 

主要产品:

Clinical Diagnostics (human)

Clinical Diagnostics (veterinary)

Food Analytics / Safety

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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艾美捷科技特约代理Biocytex品牌产品。

法国Biocytex公司一直致力于流式细胞术检测试剂的研究,其产品的特点包括:血小板分析使用全血样本进行检测;样本处理过程中不会引起血小板激活;全程免洗;样本用量少;操作简便、快捷;采用独特的定量技术,可以准确定量细胞表面特定蛋白分子或受体的数量。

 

法国Biocytex公司研发的一系列关于血小板方面的定量流式全血细胞检测试剂盒,对监控抗血小板药物和协助诊断血小板错乱疾病起到了积极作用。而同样的定量检测技术也应用于白细胞和红细胞受体分析,这些试剂盒的生产对阵发性睡眠症(PNH)提供诊断标准。

 

Created in the early 90's BioCytex a French biotech company became part of the Stago Group in 1994. BioCytex affiliate is specialised in the development of standardised flow cytometry kits in the field of Haemostasis. Since the foundation of BioCytex in the close proximity of the University and Hospital Complex of La Timone / La Conception in Marseille (France), the need of standardisation in flow cytometry analysis still remains a topic of concern. Inter-laboratory reproducibility, day to day reproducibility and positivity and/or negativity threshold determination are a real need that can be addressed by the use of quantitative flow cytometry application kits. This is the expertise offered by BioCytex. After the success of our first generation of products with the QIFIKIT, we strove to improve and tune our quantitative flow cytometry technology and applied it to the analysis of platelets (PLATELET line), leukocytes and red blood cells (CELLQUANT / REDQUANT lines).

 

Biocytex公司的主要产品包括:

应用于流式细胞术17类(其中血小板10种)

用于分子生物学5类

ELISA试剂盒3类(包括检测重组细胞因子CD146)

抗体共计56种,其中CD抗体共有49种

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艾美捷科技代理42 life sciences品牌全系列产品


42 life sciences是一家位于德国北部不来梅港的中小型企业。42 life sciences专注于开发和生产用于免疫组化(IHC)及原位杂交(ISH)应用的创新试剂。公司的核心优势在于拥有经验丰富的生物技术专家团队,确保产品开发高效聚焦,同时以可靠且具成本效益的方式进行生产。所有研发与制造流程均在我们自有设施中严格遵循EN ISO9001和EN ISO 13485标准执行。

42 life sciences公司的产品与服务包括:免疫组化与原位杂交创新试剂;外包生物缓冲液及试剂的生产业务。


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▎42 life sciences产品列表

分类品名产品描述货号规格
Chromogens for HRPAEC Solution IHC (ready-to-use)AEC (3-Amino-9-Ethylcarbazole) is a commonly used chromogen for immunohistochemical (IHC) procedures supplied in one liquid component.S-99012-100;S-99012-1000100ml;1000ml
Chromogens for HRPAEC Solution ISH (ready-to-use)AEC (3-Amino-9-Ethylcarbazole) is a commonly used chromogen for chromogenic in situ hybridization (CISH) procedures supplied in one liquid component.S-99010-500;S-99010-1000500ml;1000ml
Chromogens for HRPDAB Solution Set (2 components)DAB (3,3‘-diaminobenzidine) is a widely used chromogen in immunohistochemical and immunoblotting applications.S-99014-103;S-99014-1030103ml;1030ml
Chromogens for HRPHRP-Green Solution Set (2 components)The HRP-Green Solution Set is a new chromogen used in immunohistochemical and chromogenic in situ hybridization applications.S-99056-103;S-99056-1030103ml;1030ml
Chromogens for HRPHRP-Green Solution Set (MxE)The HRP-Green Solution Set (MxE) is a unique chromogen used in immunohistochemical and chromogenic in situ hybridization applications that is mixable in equal parts.S-99070-100;S-99070-2000100ml;2000ml
Chromogens for HRPAP-Red Solution Set IHC (2 components)The AP-Red Solution Set IHC is a chromogen used in immunohistochemical applications.S-99065-103103ml
Chromogens for HRPAP-Red Solution Set ISH (2 components)The AP-Red Solution Set ISH is a chromogen used in chromogenic in situ hybridization applications.S-99061-10301030ml
Chromogens for HRPNBT/BCIP Solution (ready-to-use)The NBT/BCIP Solution is a chromogen used in immunohistochemical and chromogenic in situ hybridization applications.S-99064-500500ml
CounterstainsMayer`s Hematoxylin Solution (ready-to-use)Mayer’s Hematoxylin Solution is a staining reagent for histological applications.S-99025-10001000ml
CounterstainsNuclear Blue Solution (ready-to-use)Nuclear Blue Solution is a hematoxylin based reagent for counterstaining applications in in situ hybridization (ISH) and immunohistochemistry (IHC) procedures using common chromogens like AEC and DAB.S-99035-10001000ml
CounterstainsNuclear Fast Red Solution (ready-to-use)Nuclear Fast Red Solution is designed for use as a counterstaining solution in immunohistochemistry (IHC) procedures using common chromogens like BCIP/NBT.S-99031-10001000ml
CounterstainsNuclear Red Solution (ready-to-use)Nuclear Red Solution is a nuclear fast red (a.k.a. Kernechtrot) based reagent for counterstaining applications in in situ hybridization (ISH) and immunohistochemistry (IHC) procedures.S-99033-500;S-99033-1000500ml;1000ml
CounterstainsNuclear Green Solution (ready-to-use)Ready-to-use Nuclear Green Solution optimized for the use in immunohistochemical (IHC) and in situ hybrididzation (ISH) procedures. Suitable for aqueous and non- aqueous mountants.S-99104-10001000ml
Ancillary Reagents1% BSA Ab Diluent (ready-to-use)The 1% BSA Ab Diluent is a stabilizer and diluent for all antibodies routinely used in immunohistochemistry (IHC) and in situ hybridization (ISH) applications.S-99068-10001000ml
Ancillary Reagentsone4all-Antibody Stabilizer (ready-to-use)The one4all-Antibody Stabilizer is a unique stabilizer for all antibody-enzyme conjugates routinely used in immunohistochemistry (IHC) and in situ hybridization (ISH) applications as well as in ELISA.S-99030-10001000ml
Ancillary ReagentsPepsin Solution (ready-to-use)Pepsin is a commonly used digestive enzyme for immunohistochemical (IHC) and in situ hybridization (ISH) procedures.S-99003-50;S-99003-500;S-99003-100050ml;500ml;1000ml
Ancillary ReagentsPepsin Solution for Cytology (ready-to-use)Pepsin Solution for Cytology is a digestive enzyme solution used in in situ hybridization (ISH) procedures in cytology specimens.S-99053-500;S-99053-1000500ml;1000ml
Ancillary ReagentsProteinase K Solution (ready-to-use)The Proteinase K Solution is specifically designed for use in the pretreatment of formalin-fixed tissue for in situ-hybridization (ISH) procedures.S-99080-100100ml
Ancillary ReagentsDuraTect™ DAPI/Antifade Solution (ready-to-use)The DuraTect™ DAPI/Antifade Solution is a refrigerator-stable formula for preserving fluorescence.S-99081-10;S-99081-100;S-99081-50010ml;100ml;500ml
Ancillary ReagentsDuraTect™ DAPI/Antifade Solution "ultra" (ready-to-use)The DuraTect™ DAPI/Antifade Solution "ultra" is a refrigerator-stable formula for preserving fluorescence.S-99098-5050ml
Ancillary ReagentsCOT-DNA, human (10mg/ml)The COT fraction of human genomic DNA predominantly consists of rapidly annealing repetitive sequences.S-99040-1;S-99040-10;S-99040-501mg;10mg;50mg



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BiosPacific公司是R&D Systems 旗下专门为临床诊断试剂的研发与生产提供抗原、抗体(多抗、单抗、偶联的抗体、抗体对)的公司,在临床诊断试剂方面非常著名,是临床诊断试剂原料的全球供应商。BiosPacific公司是全球著名的临床诊断抗原抗体原料的供应商,其产品主要集中在癌症(肿瘤)、内分泌、传染病、人血清蛋白、甾类、血管病等标记物的优质单抗、多抗、抗原、偶联抗体,以及抗体对(matched pairs)。

 

As a manufacturer and supplier of antibodies and antigens of exceptional quality, for more than 29 years, BiosPacific is experienced in meeting the rigorous demands of the industrial client. Our success has been due, in large part, to our commitment to find the most effective solutions for your individual needs. Our expansive range of monoclonal antibodies, affinity purified polyclonal antibodies and purified proteins for immunoassay development allows us to support our customers collaboratively from feasibility to manufacturing. Browse by subject category such as cancer or cardiac markers below, or do a keyword search using the search field above.

 

BIOSPACIFIC产品的主要涵盖领域:

(1)Cancer

AFP, Alpha-2 Macroglobulin, Beta-2 Microglobulin, CA 125

(2)Endocrine Thyroid

ACTH, FSH, hCG, hGH, IGF-1, Insulin, LH, Proinsulin

(3)Steroids

Cortisol, Estradiol, Progesterone, Testosterone

(4)Cardio-vascular

CKBB, CKMB, CKMM, CRP, D-dimer, Myoglobin, TNI

(5)Human Serum Proteins

Albumin, Alpha-1 Antitrypsin, APO E,CRP, Hemoglobin

(6)Miscellaneous

Ferritin, Glucagon, IgE Myeloma Plasma, Stripped Serums, TPO

(7)Drugs

Amikacin, Amphetamine, Barbiturate, Benzodiazepine

(8)Infectious Diseases

Adenovirus, Chlamydia, CMV, Influenza A & B, HAV, HBcAg, Zika

(9)Medix Biochemica

AFP, CEA, CKMB, IgA, Myoglobin, RSV, SHBG, TSH

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地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301

电话:18327026838

传真:15172469628

邮箱:sales@amyjet.com

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